RCL1, RNA terminal phosphate cyclase like 1, 10171

N. diseases: 19; N. variants: 43
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10815095
rs10815095
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs10815095
rs10815095
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10815095
rs10815095
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0427460
Disease:
Red cell distribution width determination 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10815095
rs10815095
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17803780
rs17803780
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17803780
rs17803780
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs460182
rs460182
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12375841
rs12375841
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0019163
Disease:
Hepatitis B 		0.010 GeneticVariation BEFREE In addition, rs12375841 and its unique haplotype (ht2) in miR-101-2 show significant association with clearance of hepatitis B virus infection. 22658643 2012
dbSNP: rs462480
rs462480
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Additionally, combined analysis of the two high-risk SNPs revealed that subjects carrying the variant genotypes of rs462480 and rs1053872 had increased risk of breast cancer in a dose-response manner (P(trend) = 0.002). 24475105 2014
dbSNP: rs462480
rs462480
Entrez Id: 10171;406894
Gene Symbol: RCL1;MIR101-2
RCL1;MIR101-2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Additionally, combined analysis of the two high-risk SNPs revealed that subjects carrying the variant genotypes of rs462480 and rs1053872 had increased risk of breast cancer in a dose-response manner (P(trend) = 0.002). 24475105 2014
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.800 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.800 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.800 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		A 0.800 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		A 0.800 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		A 0.800 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		A 0.800 GeneticVariation GWASCAT Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		A 0.800 GeneticVariation GWASCAT Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs13300663
rs13300663
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASDB New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs13300663
rs13300663
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASCAT New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs2236496
rs2236496
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		T 0.800 GeneticVariation GWASCAT GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. 23263863 2013
dbSNP: rs2236496
rs2236496
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		C 0.800 GeneticVariation GWASCAT Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs2236496
rs2236496
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		T 0.800 GeneticVariation GWASDB GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. 23263863 2013
dbSNP: rs2236496
rs2236496
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		C 0.800 GeneticVariation GWASCAT Genome-wide association study of hematological and biochemical traits in a Japanese population. 20139978 2010
dbSNP: rs423955
rs423955
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0032181
Disease:
Platelet Count measurement 		A 0.800 GeneticVariation GWASCAT A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. 24026423 2014